Right-click on the drive and select Turn on Bitlocker from the context menu. Open File Explorer to the This PC folder. After reversing the BitLocker hardware setting, software BitLocker with TPM and PIN proceeded as usual. To Turn On BitLocker for a Removable Data Drive in Windows 10, Configure the encryption method for BitLocker if required. A) At boot when prompted to plug in the USB flash drive that contains the startup key, click/tap on Press Esc for BitLocker recovery, and go to step 4 below. However, on beginning BitLocker, an error message appeared stating software encryption is not available because of the registry setting. Do step 2 or 3 below depending on what you set to unlock your OS drive with. I then enabled the local computer policy BitLocker setting "Configure use of hardware-based encryption for operating system drives" to prevent software-based encryption and enabled the setting "Require additional authentication at startup" to allow TPM + PIN.
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To configure the two together I installed a new 870 Evo SSD in a separate computer, used Samsung Magician to set SSD security to "security ready to be enabled", moved the SSD to the target computer and performed a fresh Windows 10 pro installation. To encrypt a USB drive in Windows 10, you have to start the BitLocker Drive Encryption wizard, which you can open either from File Explorer or from the Control Panel. I have previously setup software BitLocker with a startup PIN and hardware BitLocker without a PIN. Is it possible to configure Windows 10 Pro BitLocker to use the hardware encryption built into a TCG Opal 2.0 SSD and a startup PIN?